Persistent oxidative stress in colorectal carcinoma patients.

  title={Persistent oxidative stress in colorectal carcinoma patients.},
  author={Daniel Gackowski and Zbigniew Banaszkiewicz and Rafał R{\'o}żalski and Arkadiusz Jawień and Ryszard Olinski},
  journal={International journal of cancer},
  volume={101 4},
We examine whether the level of 8-oxo-2'-deoxyguanosine (8-oxodGuo) in lymphocytes DNA is higher in colon cancer when compared to the control group. Factors that may influence oxidative stress such as antioxidant vitamins and uric acid were also determined. Blood samples were obtained from a control group of 55 healthy persons and 43 colon cancers. 8-OxodGuo level and the vitamins concentration were measured by high-performance liquid chromatography. The levels of 8-oxodGuo were significantly… CONTINUE READING
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