Persistent inflammation and immune activation contribute to cholestasis in patients receiving home parenteral nutrition.

@article{Reimund2001PersistentIA,
  title={Persistent inflammation and immune activation contribute to cholestasis in patients receiving home parenteral nutrition.},
  author={J. M. Reimund and Bernard Duclos and Yves Arondel and Ren{\'e} Baumann},
  journal={Nutrition},
  year={2001},
  volume={17 4},
  pages={300-4}
}
Liver disease is frequent in patients taking home parenteral nutrition (HPN), but its cause remains unclear. Ongoing inflammation was implicated in HPN-associated cholestasis, so we examined the relation between liver-enzyme concentrations and circulating inflammatory and immune markers in these patients. In 17 HPN patients and 10 age- and sex-matched control subjects, we examined erythrocyte sedimentation rate, blood neopterin, soluble interleukin (IL)--2 receptors, circulating tumor necrosis… CONTINUE READING

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