Persistent infertility in ewes after prolonged exposure to oestradiol-17 beta.

@article{Adams1988PersistentII,
  title={Persistent infertility in ewes after prolonged exposure to oestradiol-17 beta.},
  author={Nancy R. Adams and M. Reinisch B. Runnebaum Y Sakuma S. A. Sanders},
  journal={Journal of reproduction and fertility},
  year={1988},
  volume={84 1},
  pages={373-8}
}
Merino ewes were treated with implants which released 300 micrograms oestradiol-17 beta per day or 5 mg progesterone per day, or both, for 9 months (Months 1-9), and after an 11-month intermission were treated again for 6 months (Months 20-26). Ewes were run with rams at Months 16, 28 and 40. Fertility was not affected by the first exposure period, but the second exposure to oestradiol reduced the fertility of ewes at both subsequent mating periods. Affected ewes returned to service more… CONTINUE READING