Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts.

@article{Han1990PersistentIO,
  title={Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts.},
  author={Jung Whan Han and Henry B. Sadowski and Donald B. Young and Ian G. Macara},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 9},
  pages={3373-7}
}
A BALB/c 3T3 cell line infected with the temperature-sensitive Rous sarcoma virus strain LA90 has been used to investigate early, p60v-src-dependent changes in gene expression (protein synthesis). Giant two-dimensional electrophoresis, which can resolve greater than 3000 polypeptides from [35S]methionine-labeled cell lysates, was used to detect the… CONTINUE READING