Persistent impairment of hippocampal neurogenesis in young adult rats following early postnatal alcohol exposure.

@article{Klintsova2007PersistentIO,
  title={Persistent impairment of hippocampal neurogenesis in young adult rats following early postnatal alcohol exposure.},
  author={Anna Y. Klintsova and Jennifer Lauren Helfer and Lyngine Hu Calizo and Willie K. Dong and Charles R. Goodlett and William T. Greenough},
  journal={Alcoholism, clinical and experimental research},
  year={2007},
  volume={31 12},
  pages={
          2073-82
        }
}
BACKGROUND Prenatal alcohol exposure can cause damage to the developing fetus with outcomes including growth deficiency, facial dysmorphology, brain damage, and cognitive and behavioral deficits. Smaller brains in children with FASD have been linked both with reduced cell proliferation in the developing CNS and with apoptotic cell loss of postmitotic neurons. Prenatal alcohol exposure in rodents during the period of brain development comparable to that of the first and second trimesters of… CONTINUE READING
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