Persistent fibrosis, hypertrophy and sarcomere disorganisation after endoscopy-guided heart resection in adult Xenopus

@inproceedings{Marshall2017PersistentFH,
  title={Persistent fibrosis, hypertrophy and sarcomere disorganisation after endoscopy-guided heart resection in adult Xenopus},
  author={Lindsey Marshall and C{\'e}line Vivien and Fabrice Girardot and Louise P{\'e}ricard and Barbara A Demeneix and Laurent Coen and Norin Chai},
  booktitle={PloS one},
  year={2017}
}
Models of cardiac repair are needed to understand mechanisms underlying failure to regenerate in human cardiac tissue. Such studies are currently dominated by the use of zebrafish and mice. Remarkably, it is between these two evolutionary separated species that the adult cardiac regenerative capacity is thought to be lost, but causes of this difference remain largely unknown. Amphibians, evolutionary positioned between these two models, are of particular interest to help fill this lack of… CONTINUE READING