Persistent diastolic dysfunction despite successful long-term octreotide treatment in acromegaly.

  title={Persistent diastolic dysfunction despite successful long-term octreotide treatment in acromegaly.},
  author={Sjoerd W van Thiel and Jeroen J. Bax and Nienke R Biermasz and Eduard R. Holman and Don Poldermans and Ferdinand Roelfsema and Hildo J. Lamb and E. E. van der Wall and Jan Smit and Johannes Anthonius Romijn and Alberto M Pereira},
  journal={European journal of endocrinology},
  volume={153 2},
INTRODUCTION This study was designed to evaluate potential reversibility of left-ventricular (LV) dysfunction in patients with acromegaly following long-term control of disease. It is unknown whether the cardiac changes induced by acromegaly can be reversed completely by long-term strict control of growth hormone excess by octreotide. PATIENTS AND METHODS We compared LV systolic and diastolic function in inactive patients with acromegaly (n = 22), who were divided into patients with long-term… CONTINUE READING
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Increased prevalence of regurgitant valvular heart disease in acromegaly

  • AM Pereira, SW van Thiel, +6 authors JJ. Bax
  • Journal of Clinical Endocrinology and Metabolism
  • 2004

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