Persistent behavioral impairment caused by embryonic methylphenidate exposure in zebrafish.

@article{Levin2011PersistentBI,
  title={Persistent behavioral impairment caused by embryonic methylphenidate exposure in zebrafish.},
  author={E. Levin and Damiyon Sledge and Stephanie Roach and A. Petro and Susan Donerly and E. Linney},
  journal={Neurotoxicology and teratology},
  year={2011},
  volume={33 6},
  pages={
          668-73
        }
}
As more adults take the stimulant medication methylphenidate to treat attention deficit hyperactivity disorder (ADHD) residual type, the risk arises with regard to exposure during early development if people taking the medication become pregnant. We studied the neurobehavioral effects of methylphenidate in zebrafish. Zebrafish offer cellular reporter systems, continuous visual access and molecular interventions such as morpholinos to help determine critical mechanisms underlying neurobehavioral… Expand
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