Persistent babesiosis in a Rhesus macaque (Macaca mulatta) infected with a simian-human immunodeficiency virus.

Abstract

BACKGROUND A rhesus macaque developed chronic anemia, lymphocytic leukocytopenia, fever, and anorexia while immunodeficient following inoculation with a simian-human immunodeficiency virus. METHODS A complete blood count, peripheral blood smear, polymerase chain reaction and gene sequence were performed. RESULTS Blood smears demonstrated persistent intraerythrocytic piroplasms with rare Maltese cross forms. Babesia microti-like protozoa were confirmed by polymerase chain reaction and sequencing of the 18S ribosomal RNA gene. CONCLUSION With continued use of non-human primates as models for human diseases, infection and complications from babesiosis should be monitored.

DOI: 10.1111/jmp.12105

Cite this paper

@article{Liu2014PersistentBI, title={Persistent babesiosis in a Rhesus macaque (Macaca mulatta) infected with a simian-human immunodeficiency virus.}, author={David Xianhong Liu and Amy F Gill and Patricia J. Holman and Peter J. Didier and James L. Blanchard and Ronald S Veazey and Andrew A Lackner}, journal={Journal of medical primatology}, year={2014}, volume={43 3}, pages={206-8} }