Persistent alterations of calmodulin kinase II activity in chickens after an oral dose of tri-o-cresyl phosphate.


Calmodulin kinase II has been found to be involved in the increased phosphorylation of brain microtubule and spinal cord neurofilament triplet proteins following treatment of animals with organophosphorus compounds that are capable of producing organophosphorus compound-induced delayed neurotoxicity (OPIDN). In this report, chickens were given a single oral… (More)