Persistent airflow limitation in adult-onset nonatopic asthma is associated with serologic evidence of Chlamydia pneumoniae infection.

@article{Brinke2001PersistentAL,
  title={Persistent airflow limitation in adult-onset nonatopic asthma is associated with serologic evidence of Chlamydia pneumoniae infection.},
  author={Anneke ten Brinke and Jaap Tamino van Dissel and Peter J. Sterk and Aeilko H. Zwinderman and Klaus Friedrich Rabe and Elisabeth H.D. Bel},
  journal={The Journal of allergy and clinical immunology},
  year={2001},
  volume={107 3},
  pages={449-54}
}
BACKGROUND Persistent airflow limitation may develop in patients with asthma, particularly in adults with nonatopic (intrinsic) disease. Although the underlying mechanisms are still unknown, respiratory infections might be involved. OBJECTIVE We investigated the annual loss of lung function in relation to seropositivity to Chlamydia pneumoniae in different subgroups of patients with severe asthma according to age at onset of asthma and atopic status. METHODS One hundred one nonsmoking… CONTINUE READING

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