Persistent activity in layer 5 pyramidal neurons following cholinergic activation of mouse primary cortices.

@article{Rahman2011PersistentAI,
  title={Persistent activity in layer 5 pyramidal neurons following cholinergic activation of mouse primary cortices.},
  author={Jamilur Rahman and Thomas Berger},
  journal={The European journal of neuroscience},
  year={2011},
  volume={34 1},
  pages={22-30}
}
Persistent spiking activity is thought to be a cellular process involved in working memory. We have been interested in whether persistent activity also exists in cortical areas which are not involved in this memory process. To study the possible presence and the mechanisms of persistent activity in layer 5 pyramidal cells of the mouse primary somatosensory, visual and motor cortices, we used patch-clamp and calcium imaging techniques. A combination of cholinergic receptor activation and… CONTINUE READING
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