Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast.

@article{Maleri2004PersistentAB,
  title={Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast.},
  author={Seth Maleri and Qingyuan Ge and Elizabeth A Hackett and Yuqi Wang and Henrik G. Dohlman and Beverly Errede},
  journal={Molecular and cellular biology},
  year={2004},
  volume={24 20},
  pages={9221-38}
}
Mitogen-activated protein kinase kinase kinase-Ste11 (MAPKKK-Ste11), MAPKK-Ste7, and MAPK-Kss1 mediate pheromone-induced mating differentiation and nutrient-responsive invasive growth in Saccharomyces cerevisiae. The mating pathway also requires the scaffold-Ste5 and the additional MAPK-Fus3. One contribution to specificity in this system is thought to come from stimulus-dependent recruitment of the MAPK cascade to upstream activators that are unique to one or the other pathway. To test this… CONTINUE READING

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