Persistent Zoonotic Infection of a Human with Simian Foamy Virus in the Absence of an Intact orf-2Accessory Gene

  title={Persistent Zoonotic Infection of a Human with Simian Foamy Virus in the Absence of an Intact orf-2Accessory Gene},
  author={M. Callahan and W. Switzer and A. Matthews and B. Roberts and W. Heneine and T. Folks and P. Sandstrom},
  journal={Journal of Virology},
  pages={9619 - 9624}
  • M. Callahan, W. Switzer, +4 authors P. Sandstrom
  • Published 1999
  • Biology, Medicine
  • Journal of Virology
  • ABSTRACT Although foamy viruses (FVs) are endemic among nonhuman primates, FV infection among humans is rare. Recently, simian foamy virus (SFV) infection was reported in 4 of 231 individuals occupationally exposed to primates (1.8%). Secondary transmission to spouses has not been seen, suggesting that while FV is readily zoonotic, humans may represent dead-end hosts. Among different simian species, SFV demonstrates significant sequence diversity within the U3 region of the long terminal repeat… CONTINUE READING
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