Persistent T lymphocyte rhythms despite suppressed circadian clock outputs in rats.

  title={Persistent T lymphocyte rhythms despite suppressed circadian clock outputs in rats.},
  author={Petra Depr{\'e}s-Brummer and Philippe Bourin and Nicole Pag{\`e}s and Greg Metzger and Francis L{\'e}vi},
  journal={The American journal of physiology},
  volume={273 6 Pt 2},
Circadian rhythms in circulating leukocyte and lymphocyte counts persisted with halved amplitudes in constant light (LL) of 300 lx intensity for 8 wk, whereas circadian rhythms in body temperature, locomotor activity, and plasma catecholamines were completely suppressed. Subsequent exposure to constant darkness (DD) normalized all circadian rhythms within 2 wk. Rhythms in circulating T lymphocyte subsets were studied in LL or DD using double labeling with monoclonal antibodies and flow… CONTINUE READING


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