Persistent Inflammation, Immunosuppression, and Catabolism: Evolution of Multiple Organ Dysfunction.

  title={Persistent Inflammation, Immunosuppression, and Catabolism: Evolution of Multiple Organ Dysfunction.},
  author={Martin D. Rosenthal and Fredrick Moore},
  journal={Surgical infections},
  volume={17 2},
BACKGROUND Multiple organ dysfunction (MOD) has plagued intensive care units (ICUs) for more than four decades, and its epidemiology has evolved because more patients are surviving previously lethal insults. Over the years, different predominant phenotypes of MOD have been described, all of which have consumed tremendous healthcare resources and have been associated with prolonged ICU stays and prohibitive mortality rates. METHODS Review of the English-language literature. RESULTS By the… CONTINUE READING

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