Persistence of viral infections on the population level explained by an immunoepidemiological model.

@article{Kostova2007PersistenceOV,
  title={Persistence of viral infections on the population level explained by an immunoepidemiological model.},
  author={Tanya Kostova},
  journal={Mathematical biosciences},
  year={2007},
  volume={206 2},
  pages={309-19}
}
We consider a mathematical model of viral spread in a population based on an immune response model embedded in an epidemic network model. The immune response model includes virus load and effector and memory T cells with two possible outcomes depending on parameters: (a) virus clearance and establishment of immune memory and (b) establishment of a non-zero viral presence characterized with increased T-cell concentrations. Isolated individuals can have different immune system parameters and… CONTINUE READING