Persistence of viral DNA in the epithelial basal layer suggests a model for papillomavirus latency following immune regression

@inproceedings{Maglennon2011PersistenceOV,
  title={Persistence of viral DNA in the epithelial basal layer suggests a model for papillomavirus latency following immune regression},
  author={Gareth Adam Maglennon and P. McIntosh and John Doorbar},
  booktitle={Virology},
  year={2011}
}
Rabbit oral papillomavirus (ROPV) causes benign and spontaneously regressing oral lesions in rabbits, and is a useful model of disease associated with low-risk human papillomavirus types. Here we have adapted the ROPV system to study papillomavirus latency. Following lesion regression, ROPV DNA persists at the majority of regressed sites at levels substantially lower than those found in productive papillomas. Spliced viral transcripts were also detected. ROPV persistence in the absence of… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 76 CITATIONS

FILTER CITATIONS BY YEAR

2011
2019

CITATION STATISTICS

  • 8 Highly Influenced Citations

  • Averaged 12 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 27 REFERENCES

Roles of the E6 and E7 proteins in the life cycle of low-risk human papillomavirus type 11

  • J. Virol.
  • 2004

Intraepithelial vaccination with COPV L1 DNA by particle-mediated DNA delivery protects against mucosal challenge with infectious COPV in beagle dogs

  • Vaccine
  • 2001

Similar Papers

Loading similar papers…