Persistence of varicella-zoster virus DNA in elderly patients with postherpetic neuralgia.

@article{Mahalingam1995PersistenceOV,
  title={Persistence of varicella-zoster virus DNA in elderly patients with postherpetic neuralgia.},
  author={Ragho J. Mahalingam and Mary C. Wellish and J Brucklier and Donald H. Gilden},
  journal={Journal of neurovirology},
  year={1995},
  volume={1 1},
  pages={
          130-3
        }
}
The most common complication of zoster in the elderly is postherpetic neuralgia, operationally defined as pain persisting longer than 1-2 months after rash. The cause of postherpetic neuralgia is unknown. Using polymerase chain reaction, we detected varicella zoster virus DNA in blood mononuclear cells from 11 of 51 postherpetic neuralgia patients, but not in any of 19 zoster patients without postherpetic neuralgia, or in any of 11 elderly individuals without a history of zoster. Blood… CONTINUE READING
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