Persistence of tick-borne encephalitis virus in monkeys. II. Effectiveness of methods used for virus detection.

@article{Pogodina1981PersistenceOT,
  title={Persistence of tick-borne encephalitis virus in monkeys. II. Effectiveness of methods used for virus detection.},
  author={Vanda V. Pogodina and G. V. Malenko and G. I. Fokina and Ludmila S. Levina and G. V. Koreshkova and O E Rzhakhova and Nadezshda G. Bochkova and L L Mamonenko},
  journal={Acta virologica},
  year={1981},
  volume={25 6},
  pages={344-51}
}
Fifty monkeys (Macaca rhesus) inoculated with tick-borne encephalitis (TBE)virus intracerebrally or subcutaneously were examined. The efficiencies of different virus detection methods at 90 to 783 days after inoculation were: explantation of organs - 41.2%; co-cultivation of trypsinized organ cells and indicator cells in the presence of 5-bromo-2-iododeoxyuridine with detection of the virus-specific antigen by immunofluorescence - 43.7%, detection of infectious virus and complement-fixing… CONTINUE READING