Persistence of the olfactory receptor current in a wide variety of extracellular environments.

@article{Kleene1996PersistenceOT,
  title={Persistence of the olfactory receptor current in a wide variety of extracellular environments.},
  author={Steven J. Kleene and Raymund Y. K. Pun},
  journal={Journal of neurophysiology},
  year={1996},
  volume={75 4},
  pages={1386-91}
}
We measured the current activated by cytoplasmic adenosine 3':5'-cyclic monophosphate (cAMP) in olfactory cilia from the frog Rana pipiens. The odorant-induced current in frog olfactory receptor neurons was also measured for comparison. In both cases, recordings were performed near the neuronal resting potential in a variety of extracellular bath solutions. 2. In Ca(2+)-free baths, cAMP activated an inward current in excised olfactory cilia that was carried entirely by cations. As extracellular… CONTINUE READING

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