Persistence of the interaction of calmodulin with adenylyl cyclase: implications for integration of transient calcium stimuli.

@article{Onyike1998PersistenceOT,
  title={Persistence of the interaction of calmodulin with adenylyl cyclase: implications for integration of transient calcium stimuli.},
  author={Chiadi U. Onyike and Allison H Lin and Thomas W. Abrams},
  journal={Journal of neurochemistry},
  year={1998},
  volume={71 3},
  pages={1298-306}
}
Ca2+/calmodulin-sensitive adenylyl cyclase plays a role in several forms of synaptic plasticity and learning. To understand how cellular signals from neuronal activity during behavioral stimuli might be integrated by adenylyl cyclase, we have characterized the response of type I adenylyl cyclase to transient Ca2+ stimuli. Stimulation by a several second Ca2… CONTINUE READING