Persistence of neutralizing antibodies after discontinuation of IFNbeta therapy in patients with relapsing-remitting multiple sclerosis.

@article{Petersen2006PersistenceON,
  title={Persistence of neutralizing antibodies after discontinuation of IFNbeta therapy in patients with relapsing-remitting multiple sclerosis.},
  author={Bodil Laub Petersen and Klaus Bendtzen and Nils J Koch-Henriksen and Mads Ravnborg and Christian Ross and Per Soelberg Sorensen},
  journal={Multiple sclerosis},
  year={2006},
  volume={12 3},
  pages={247-52}
}
OBJECTIVE The main objective was to follow serum levels of neutralizing antibodies (NABs) against interferon-beta (IFNbeta) after discontinuation of IFNbeta therapy. BACKGROUND A large proportion of patients treated with recombinant IFNbeta for multiple sclerosis (MS) develop therapy-induced NABs. Knowledge of persistence of NABs after discontinuation of therapy is limited. DESIGN/PATIENTS A retrospective follow-up study of patients treated in Denmark for relapsing remitting (RR) MS with… CONTINUE READING