Persistence of lysergic acid diethylamide in the plasma of human subjects

@article{Aghajanian1964PersistenceOL,
  title={Persistence of lysergic acid diethylamide in the plasma of human subjects},
  author={G. Aghajanian and O. H. Bing},
  journal={Clinical Pharmacology & Therapeutics},
  year={1964},
  volume={5}
}
  • G. Aghajanian, O. H. Bing
  • Published 1964
  • Chemistry, Medicine
  • Clinical Pharmacology & Therapeutics
  • Two micrograms per kilogram of LSD‐25 was administered intravenously to five normal human subjects. The concentration of drug in plasma was determined serially over the subsequent 8 hours. LSD‐25 was found to be present in human plasma in relatively large quantities during the period of peak effect. The half‐life of LSD‐25 in human plasma was calculated to be 175 minutes. 
    110 Citations

    Topics from this paper.

    The determination of LSD in human plasma following oral administration.
    • 34
    The fate of LSD in the body: forensic considerations.
    • 13
    Pharmacokinetics and Concentration-Effect Relationship of Oral LSD in Humans
    • 52
    • Highly Influenced
    • PDF
    Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects
    • 27
    • PDF
    Body fluid levels of lysergide (LSD).
    • 15

    References

    SHOWING 1-8 OF 8 REFERENCES
    THE DISTRIBUTION AND METABOLISM OF LYSERGIC ACID DIETHYLAMIDE
    • 140
    • PDF
    A REVIEW OF THE CLINICAL EFFECTS OF PSYCHOTOMIMETIC AGENTS
    • H. Osmond
    • Medicine
    • Annals of the New York Academy of Sciences
    • 1957
    • 175
    Mescaline, LSD, psilocybin, and personality change.
    • 22
    • PDF
    Distribution and fate of C " labeled lysergic acid diethylamide (LSD-25) in the animal body, Experientia
    • 1955
    Distribution and fate of C14_ labeled lysergic acid diethylamide (LSD-25) in the animal
    • body, Experientia
    • 1955
    THE EFFECTS OF D‐LYSERGIC ACID DIETHYLAMIDE ON CEREBRAL CIRCULATION AND OVER‐ALL METABOLISM
    • 48
    The distribution and metabolism of lysergic acid diethylamide, Ann
    • New York Acad Sc
    • 1957