Persistence of immunoreactive neurofilament protein breakdown products in transected rat sciatic nerve.

@article{Schlaepfer1984PersistenceOI,
  title={Persistence of immunoreactive neurofilament protein breakdown products in transected rat sciatic nerve.},
  author={William W. Schlaepfer and C G Lee and J. Q. Trojanowski and V M.-Y. Lee},
  journal={Journal of neurochemistry},
  year={1984},
  volume={43 3},
  pages={857-64}
}
Alterations occurring in nerve proteins of transected nerves were studied in rat sciatic nerves using polyclonal and monoclonal antibodies to identify and monitor neurofilament (NF) epitopes among nerve proteins following their electrophoresis and transfer to nitrocellulose paper. Immunoblot methods identified NF epitopes in NF triplet proteins (Mr 200,000, 150,000, and 68,000) and in NF nontriplet proteins (all other immunobands below Mr 200,000 and above Mr 40,000). NF triplet and nontriplet… CONTINUE READING
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