Persistence of immunity after vaccination with a capsular group B meningococcal vaccine in 3 different toddler schedules.

@article{Sadarangani2017PersistenceOI,
  title={Persistence of immunity after vaccination with a capsular group B meningococcal vaccine in 3 different toddler schedules.},
  author={Manish Sadarangani and Tim Sell and Mildred Adaku Iro and Matthew D Snape and Merryn Voysey and Adam Finn and Paul Trafford Heath and G. Delgado Bona and Susanna Esposito and Javier D{\'i}ez-Domingo and Roman Prymula and Adefowope Odueyungbo and Daniela Toneatto and Andrew J. Pollard},
  journal={CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne},
  year={2017},
  volume={189 41},
  pages={
          E1276-E1285
        }
}
BACKGROUND One schedule for the capsular group B meningococcal vaccine 4CMenB is 2 doses that are administered 2 months apart for children aged 12-23 months, with a booster dose 12-24 months later. Our objective was to provide data on persistence of human serum bactericidal antibody (hSBA) titres in children up to 4 years of age after initial doses at 12-24 months, and immunogenicity of a booster dose at 48 months of age compared with vaccine-naive children. METHODS Children previously… CONTINUE READING
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