Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells.

@article{Saito2010PersistenceOD,
  title={Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells.},
  author={Toshiki I. Saito and Joji Fujisaki and Alicia L. Carlson and Charles P. Lin and Megan Sykes},
  journal={Experimental hematology},
  year={2010},
  volume={38 4},
  pages={333-9}
}
OBJECTIVE In recipients of allogeneic hematopoietic stem cell transplantation to treat hematologic malignancies, we have unexpectedly observed anti-tumor effects in association with donor cell rejection in both mice and humans. Host-type CD8 T cells were shown to be required for these anti-tumor effects in the murine model. Because sustained host CD8 T-cell… CONTINUE READING