Persistence of coronary vasodilator reserve despite functionally significant flow reduction.

@article{Aversano1985PersistenceOC,
  title={Persistence of coronary vasodilator reserve despite functionally significant flow reduction.},
  author={Thomas R Aversano and Lewis C. Becker},
  journal={The American journal of physiology},
  year={1985},
  volume={248 3 Pt 2},
  pages={H403-11}
}
This study was done to determine whether coronary vasodilator reserve is exhausted when coronary flow falls and regional function becomes abnormal during low-pressure perfusion. In 10 open-chest, anesthetized dogs the left circumflex coronary artery (LC) was cannulated and perfused via a blood-filled reservoir. At LC pressures of 35 and 50 mmHg, regional segment lengths were measured with sonomicrometer crystals and regional flow with radiolabeled microspheres before and after adenosine… CONTINUE READING
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