Persistence of antineutrophil cytoplasmic antibodies (ANCA) in asymptomatic patients with systemic polyarteritis nodosa or Churg-Strauss syndrome: follow-up of 53 patients.

@article{Cohen1995PersistenceOA,
  title={Persistence of antineutrophil cytoplasmic antibodies (ANCA) in asymptomatic patients with systemic polyarteritis nodosa or Churg-Strauss syndrome: follow-up of 53 patients.},
  author={Pascal Cohen and Lo{\"i}c Guillevin and Laurene L Baril and François Lhote and Laure H{\'e}l{\`e}ne Noel and Philippe Lesavre},
  journal={Clinical and experimental rheumatology},
  year={1995},
  volume={13 2},
  pages={193-8}
}
OBJECTIVE We retrospectively analyzed the significance of persistent ANCA positivity after clinical remission in 53 consecutive patients with histologically and/or angiographically proven polyarteritis nodosa (PAN), or Churg-Strauss syndrome (CSS) followed between 1981 and 1993. METHODS ANCA were detected using an immunofluorescence assay and ELISA: Each patient met the American College of Rheumatology 1990 criteria for PAN or CSS. Clinical and biological evaluations were always essential… CONTINUE READING