Persistence and expansion of cryptic endangered red wolf genomic ancestry along the American Gulf coast.

  title={Persistence and expansion of cryptic endangered red wolf genomic ancestry along the American Gulf coast.},
  author={Bridgett M. vonHoldt and Kristin E. Brzeski and Matthew L. Aardema and Christopher Schell and Linda Y Rutledge and Steven R. Fain and Amy C Shutt and Anna Linderholm and William J. Murphy},
  journal={Molecular ecology},
Admixture and introgression play a critical role in adaptation and genetic rescue that has only recently gained a deeper appreciation. Here, we explored the geographic and genomic landscape of cryptic ancestry of the endangered red wolf that persists within the genome of a ubiquitous sister taxon, the coyote, all the while the red wolf has been extinct in the wild since the early 1980s. We assessed admixture across 120,621 SNP loci genotyped in 293 canid genomes. We found support for increased… 


A Genome-wide perspective on the persistence of red wolf ancestry in southeastern canids.
This study examines geographic and temporal patterns of genome-wide red wolf ancestry in 260 canids across the southeastern United States at over 164,000 SNP loci and finds that redWolf ancestry was most prevalent in canids sampled from Texas in the mid-1970s, although non-trivial amounts of redwolf ancestry persisted in this region today.
A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids.
It is found that these enigmatic canids are highly admixed varieties derived from gray wolves and coyotes, respectively, and divergent genomic history suggests that they do not have a shared recent ancestry as proposed by previous researchers.
Demographic history influences spatial patterns of genetic diversityin recently expanded coyote (Canis latrans) populations
A genetic survey at 10 microsatellite loci of 482 coyotes originating from 11 eastern U.S. states found that population structure corresponded to a north–south divide, which is consistent with the two known expansion routes, and observed extremely high genetic diversity, atypical of recently expanded populations.
Functional consequences of archaic introgression and their impact on fitness
Recent findings on how natural selection—either negative or positive— has shaped the landscape of Neanderthal ancestry in the genomes of modern Eurasians are discussed, and the contribution of archaic haplotypes to present-day phenotypic variation is commented on.
Admixture mapping identifies introgressed genomic regions in North American canids
It is shown that grey wolf and coyote admixture has far‐reaching effects and, in addition to phenotypically transforming admixed populations, allows for the differential movement of alleles from different parental species to be tested in new genomic backgrounds.
Whole-genome sequence analysis shows that two endemic species of North American wolf are admixtures of the coyote and gray wolf
Genome admixture in two endemic North American wolf species. Protection of populations comprising admixed genomes is a challenge under the Endangered Species Act (ESA), which is regarded as the most
Population Genomic Analysis of North American Eastern Wolves (Canis lycaon) Supports Their Conservation Priority Status
A population genomics approach is used to uncover spatial patterns of variation in 281 canids in central Ontario and the Great Lakes region, which represents the first genome-wide single nucleotide polymorphism (SNP) dataset with substantial sample sizes of representative populations.
Assessment of coyote–wolf–dog admixture using ancestry‐informative diagnostic SNPs
This study is the most comprehensive genetic survey of admixture in eastern coyotes and demonstrates that the frequency and scope of hybridization can be quantified with relatively few ancestry‐informative markers.
Rediscovery of Red Wolf Ghost Alleles in a Canid Population Along the American Gulf Coast
This report reports the rediscovery of red wolf ghost alleles in a canid population on Galveston Island, Texas, which introduces both positive opportunities for additional conservation action and difficult policy challenges.
Y-chromosome evidence supports widespread signatures of three-species Canis hybridization in eastern North America
By combining Y-chromosome and mtDNA distributional patterns, hybrid genomes of eastern wolf, coyote, gray wolf, and potentially dog origin are identified in Canis populations of central and eastern North America.