Peroxisome proliferator-activated receptors ligands and ischemia-reperfusion injury

@article{Paola2007PeroxisomePR,
  title={Peroxisome proliferator-activated receptors ligands and ischemia-reperfusion injury},
  author={Rosanna di Paola and Salvatore Cuzzocrea},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2007},
  volume={375},
  pages={157-175}
}
  • Rosanna di Paola, Salvatore Cuzzocrea
  • Published in
    Naunyn-Schmiedeberg's…
    2007
  • Chemistry, Medicine
  • Peroxisome proliferator-activated receptors (PPARs) belong to a subfamily of transcription nuclear factors. Three isoforms of PPARs have been identified: α, β/δ and γ, encoded by different genes and distributed in various tissues. They play important roles in metabolic processes like regulation of glucose and lipid redistribution. They also have anti-atherogenic, anti-inflammatory as well as antihypertensive functions. There is good evidence that ligands of PPARs reduce tissue injury associated… CONTINUE READING

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