Peroxisome proliferator-activated receptors for hypertension.

@article{Usuda2014PeroxisomePR,
  title={Peroxisome proliferator-activated receptors for hypertension.},
  author={Daisuke Usuda and Tsugiyasu Kanda},
  journal={World journal of cardiology},
  year={2014},
  volume={6 8},
  pages={
          744-54
        }
}
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear receptor superfamily, which is composed of four members encoded by distinct genes (α, β, γ, and δ). The genes undergo transactivation or transrepression under specific mechanisms that lead to the induction or repression of target gene expression. As is the case with other nuclear receptors, all four PPAR isoforms contain five or six structural regions in four functional… CONTINUE READING

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