Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells.

@article{Marx2004PeroxisomePR,
  title={Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells.},
  author={N. Marx and H. Duez and J. Fruchart and B. Staels},
  journal={Circulation research},
  year={2004},
  volume={94 9},
  pages={
          1168-78
        }
}
A large body of data gathered over the past couple of years has identified the peroxisome proliferator-activated receptors (PPAR) alpha, gamma, and beta/delta as transcription factors exerting modulatory actions in vascular cells. PPARs, which belong to the nuclear receptor family of ligand-activated transcription factors, were originally described as gene regulators of various metabolic pathways. Although the PPARalpha, gamma, and beta/delta subtypes are approximately 60% to 80% homologous in… Expand
Peroxisome proliferator-activated receptors and cardiovascular remodeling.
  • E. Schiffrin
  • Biology, Medicine
  • American journal of physiology. Heart and circulatory physiology
  • 2005
International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors
Peroxisome proliferator-activated receptors and the vascular system: beyond their metabolic effects.
Antihypertensive effects of peroxisome proliferator-activated receptor-β/δ activation.
PPARs and their Effects on the Cardiovascular System
  • A. Oyekan
  • Chemistry, Medicine
  • Clinical and experimental hypertension
  • 2011
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