Peroxisome proliferator-activated receptors: roles in tumorigenesis and chemoprevention in human cancer.

@article{Park2001PeroxisomePR,
  title={Peroxisome proliferator-activated receptors: roles in tumorigenesis and chemoprevention in human cancer.},
  author={Ben Ho Park and Benjamin N. Breyer and Tomlinson Chun He},
  journal={Current opinion in oncology},
  year={2001},
  volume={13 1},
  pages={
          78-83
        }
}
Peroxisome proliferator-activated receptors are nuclear receptors that were isolated for their ability to modulate lipid metabolism. Similar to other members of the nuclear receptor family, peroxisome proliferator-activated receptors bind ligand as heterodimers and exert their effects via transcriptional regulation through their DNA binding domains. During the past decade, it has become clear that peroxisome proliferator-activated receptors also contribute to a variety of different biologic… CONTINUE READING

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