Peroxisome proliferator-activated receptor-gamma coactivator-1alpha polymorphism is not associated with essential hypertension and type 2 diabetes mellitus in Chinese population.

@article{Chen2004PeroxisomePR,
  title={Peroxisome proliferator-activated receptor-gamma coactivator-1alpha polymorphism is not associated with essential hypertension and type 2 diabetes mellitus in Chinese population.},
  author={Shufeng Chen and Weili Yan and Jianfeng Huang and Wenjie Yang and Dongfeng Gu},
  journal={Hypertension research : official journal of the Japanese Society of Hypertension},
  year={2004},
  volume={27 11},
  pages={813-20}
}
To investigate whether variations in the peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) are associated with essential hypertension and type 2 diabetes in a Chinese population. A case-control study design was applied in a Chinese population. Two single nucleotide polymorphisms (SNPs), +1302G>A and G482S, in the PGC-1alpha gene were genotyped and compared between 494 unrelated Chinese subjects with essential hypertension and type 2 diabetes and 555 normal control… CONTINUE READING