Peroxisome proliferator-activated receptor-gamma regulates airway epithelial cell activation.

@article{Wang2001PeroxisomePR,
  title={Peroxisome proliferator-activated receptor-gamma regulates airway epithelial cell activation.},
  author={Angela Wang and Xudong Dai and Brigitte Luu and Douglas J. Conrad},
  journal={American journal of respiratory cell and molecular biology},
  year={2001},
  volume={24 6},
  pages={
          688-93
        }
}
The peroxisome proliferator-activated receptors (PPARs) are nuclear hormone transcription factors that regulate genes associated with lipid and glucose metabolism. Recent evidence suggests that PPAR-gamma may also act as a negative immunomodulator. To investigate the potential role of PPAR-gamma in regulating airway inflammation, we characterized the expression and function of PPAR-gamma in airway epithelial cells. Airway epithelial cells constitutively express PPAR-gamma-specific messenger RNA… CONTINUE READING

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