Peroxisome proliferator-activated receptor beta regulates acyl-CoA synthetase 2 in reaggregated rat brain cell cultures.

@article{BasuModak1999PeroxisomePR,
  title={Peroxisome proliferator-activated receptor beta regulates acyl-CoA synthetase 2 in reaggregated rat brain cell cultures.},
  author={Sharmila Basu-Modak and Olivier Braissant and Pascal Escher and B{\'e}atrice Desvergne and Paul Honegger and Walter Wahli},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 50},
  pages={35881-8}
}
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that regulate the expression of many genes involved in lipid metabolism. The biological roles of PPARalpha and PPARgamma are relatively well understood, but little is known about the function of PPARbeta. To address this question, and because PPARbeta is expressed to a high level in the developing brain, we used reaggregated brain cell cultures prepared from dissociated fetal rat telencephalon as experimental… CONTINUE READING

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