Peroxisome proliferator-activated receptor alpha regulates skin inflammation and humoral response in atopic dermatitis.


BACKGROUND The peroxisome proliferator-activated receptors (PPARs) alpha, beta/delta, and gamma are ligand-activated transcription factors belonging to the nuclear receptor superfamily. In addition to their regulatory role on lipid and glucose metabolism, they exert anti-inflammatory properties. In skin both PPAR-alpha and PPAR-beta/delta regulate… (More)
DOI: 10.1016/j.jaci.2007.12.1165


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