Peroxisome proliferator-activated receptor α target genes

@article{Mandard2003PeroxisomePR,
  title={Peroxisome proliferator-activated receptor α target genes},
  author={S. Mandard and M. M{\"u}ller and S. Kersten},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2003},
  volume={61},
  pages={393-416}
}
Peroxisome proliferator-activated receptors (PPARs) are nuclear proteins that belong to the superfamily of nuclear hormone receptors. They mediate the effects of small lipophilic compounds such as long-chain fatty acids and their derivatives on transcription of genes commonly called PPAR target genes. Here we review the involvement of PPARα in peroxisomal and mitochondrial fatty acid oxidation, microsomal fatty acid hydroxylation, lipoprotein, bile and amino acid metabolism, glucose homeostasis… Expand
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References

SHOWING 1-10 OF 206 REFERENCES
Differential Activation of Peroxisome Proliferator-activated Receptors by Eicosanoids (*)
The peroxisome proliferator‐activated receptor α regulates amino acid metabolism
  • S. Kersten, S. Mandard, +4 authors W. Wahli
  • Biology, Medicine
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2001
Alterations in Lipoprotein Metabolism in Peroxisome Proliferator-activated Receptor α-deficient Mice*
...
1
2
3
4
5
...