Peroxisome proliferator‐activated receptors in cutaneous biology

@article{Kuenzli2003PeroxisomePR,
  title={Peroxisome proliferator‐activated receptors in cutaneous biology},
  author={S. Kuenzli and J. Saurat},
  journal={British Journal of Dermatology},
  year={2003},
  volume={149}
}
Summary  Peroxisome proliferator‐activated receptors (PPARs) are ligand‐activated transcription factors that regulate the expression of target genes involved in many cellular functions including cell proliferation, differentiation and immune/inflammation response. The PPAR subfamily consists of three isotypes: PPARα, PPARβ/δ and PPARγ, which have all been identified in keratinocytes. PPARβ/δ is the predominant subtype in human keratinocytes, whereas PPARα and PPARγ are expressed at much lower… Expand
115 Citations
Peroxisome Proliferator-Activated Receptors (PPARs) and the Human Skin
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