Peroxisomal beta-oxidation--a metabolic pathway with multiple functions.

  title={Peroxisomal beta-oxidation--a metabolic pathway with multiple functions.},
  author={Yves Poirier and Vasily D. Antonenkov and Tuomo Glumoff and J Kalervo Hiltunen},
  journal={Biochimica et biophysica acta},
  volume={1763 12},
Fatty acid degradation in most organisms occurs primarily via the beta-oxidation cycle. In mammals, beta-oxidation occurs in both mitochondria and peroxisomes, whereas plants and most fungi harbor the beta-oxidation cycle only in the peroxisomes. Although several of the enzymes participating in this pathway in both organelles are similar, some distinct physiological roles have been uncovered. Recent advances in the structural elucidation of numerous mammalian and yeast enzymes involved in beta… CONTINUE READING

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