Peroxiredoxin 1/2 protects brain against H2O2‐induced apoptosis after subarachnoid hemorrhage

@article{Lu2019Peroxiredoxin1P,
  title={Peroxiredoxin 1/2 protects brain against H2O2‐induced apoptosis after subarachnoid hemorrhage},
  author={Yue Lu and Xiang-Sheng Zhang and Xiao-ming Zhou and Yongyue Gao and Chunlong Chen and Jing-peng Liu and Zhennan Ye and Zi-huan Zhang and Ling-Yun Wu and Wei Li and Chunhua Hang},
  journal={The FASEB Journal},
  year={2019},
  volume={33},
  pages={3051 - 3062}
}
Recent studies suggest that peroxiredoxin1/2 (Prx1/2) may be involved in the pathophysiology of post‐ischemic inflammatory responses in the brain. In this study, we assessed the distribution and function of Prx1/2 in mice after experimental subarachnoid hemorrhage (SAH). We investigated the distribution of Prx1/2 in the brains of mice both in vivo and in vitro using immunofluorescence staining. The expression of Prx1/2 after SAH was determined by Western blot. Adenanthin was used to inhibit… Expand
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