Peroxide stress elicits adaptive changes in bacterial metal ion homeostasis.

  title={Peroxide stress elicits adaptive changes in bacterial metal ion homeostasis.},
  author={Melinda J Faulkner and John D. Helmann},
  journal={Antioxidants & redox signaling},
  volume={15 1},
Exposure to hydrogen peroxide (H(2)O(2)) and other reactive oxygen species is a universal feature of life in an aerobic environment. Bacteria express enzymes to detoxify H(2)O(2) and to repair the resulting damage, and their synthesis is typically regulated by redox-sensing transcription factors. The best characterized bacterial peroxide-sensors are Escherichia coli OxyR and Bacillus subtilis PerR. Analysis of their regulons has revealed that, in addition to inducible detoxification enzymes… CONTINUE READING
39 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 39 extracted citations

Similar Papers

Loading similar papers…