Peroxide stress elicits adaptive changes in bacterial metal ion homeostasis.

@article{Faulkner2011PeroxideSE,
  title={Peroxide stress elicits adaptive changes in bacterial metal ion homeostasis.},
  author={Melinda J Faulkner and John D. Helmann},
  journal={Antioxidants & redox signaling},
  year={2011},
  volume={15 1},
  pages={175-89}
}
Exposure to hydrogen peroxide (H(2)O(2)) and other reactive oxygen species is a universal feature of life in an aerobic environment. Bacteria express enzymes to detoxify H(2)O(2) and to repair the resulting damage, and their synthesis is typically regulated by redox-sensing transcription factors. The best characterized bacterial peroxide-sensors are Escherichia coli OxyR and Bacillus subtilis PerR. Analysis of their regulons has revealed that, in addition to inducible detoxification enzymes… CONTINUE READING
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