Peroxide-induced cell death and lipid peroxidation in C6 glioma cells.

  title={Peroxide-induced cell death and lipid peroxidation in C6 glioma cells.},
  author={Arne H Linden and Michael G{\"u}lden and H Martin and Edmund Maser and H Edward Seibert},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  volume={22 5},
Peroxides are often used as models to induce oxidative damage in cells in vitro. The aim of the present study was to elucidate the role of lipid peroxidation in peroxide-induced cell death. To this end (i) the ability to induce lipid peroxidation in C6 rat astroglioma cells of hydrogen peroxide (H2O2), cumene hydroperoxide (CHP) and t-butyl hydroperoxide (t-BuOOH) (ii) the relation between peroxide-induced lipid peroxidation and cell death in terms of time and concentration dependency and (iii… CONTINUE READING


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