Perorally active nanomicellar formulation of quercetin in the treatment of lung cancer

@inproceedings{Tan2012PerorallyAN,
  title={Perorally active nanomicellar formulation of quercetin in the treatment of lung cancer},
  author={B. Tan and Yuanjie Liu and Kai-Lun Chang and Bennie KW Lim and Gigi Nc Chiu},
  booktitle={International journal of nanomedicine},
  year={2012}
}
BACKGROUND Realizing the therapeutic benefits of quercetin is mostly hampered by its low water solubility and poor absorption. In light of the advantages of nanovehicles in the delivery of flavanoids, we aimed to deliver quercetin perorally with nanomicelles made from the diblock copolymer, polyethylene glycol (PEG)-derivatized phosphatidylethanolamine (PE). METHODS Quercetin-loaded nanomicelles were prepared by using the film casting method, and were evaluated in terms of drug incorporation… CONTINUE READING
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