Peroral endoscopic myotomy compared with pneumatic dilation for newly diagnosed achalasia

@article{Meng2017PeroralEM,
  title={Peroral endoscopic myotomy compared with pneumatic dilation for newly diagnosed achalasia},
  author={Fandong Meng and Peng Li and Yong-jun Wang and Ming Ji and Yong-dong Wu and Li Yu and Ying-lin Niu and Fu-jing Lv and Wei Li and Wen-yan Li and Huihong Zhai and Shanshan Wu and Shutian Zhang},
  journal={Surgical Endoscopy},
  year={2017},
  volume={31},
  pages={4665-4672}
}
BackgroundThis study retrospectively compared the safety and efficacy of two endoscopic techniques for treating newly diagnosed achalasia, pneumatic dilation (PD), and peroral endoscopic myotomy (POEM).MethodsDemographics, clinical and manometric data, and outcomes were collected from the medical records of patients who received POEM or PD as the primary therapy for achalasia at our hospital from January 2012 to August 2015.ResultsOf 72 patients, 32 and 40 received POEM and PD, respectively… 

Peroral endoscopic myotomy versus pneumatic dilation for achalasia: a systematic review and meta-analysis

TLDR
The current evidence suggests that the long-term efficacy of POEM was superior to that of pneumatic dilation, but accompanied by higher complications.

Outcome of peroral endoscopic myotomy (POEM) in treatment-naive patients. A systematic review

TLDR
A more systematic and standardized evaluation is recommended to improve the reports on outcome of POEM and the follow-up rate should be high and the evaluation protocol should include both symptom scoring and objective testing with predefined treatment goals.

Peroral endoscopic myotomy (POEM) vs pneumatic dilation (PD) in treatment of achalasia: A meta-analysis of studies with ≥ 12-month follow-up

TLDR
POEM is more efficacious than PD in the treatment of patients with achalasia during short-term and long-term follow-up, albeit with higher risk of abnormal esophageal acid exposure.

Clinical outcomes of peroral endoscopic myotomy for achalasia in children: a systematic review and meta-analysis.

TLDR
It is demonstrated that the POEM was an effective and safe technique for treating achalasia in children and further randomized comparative studies of POEM and other therapeutic methods are warranted to determine the most effective treatment modality for achalAsia in children.

Is peroral endoscopic myotomy (POEM) more effective than pneumatic dilation and Heller myotomy? A systematic review and meta-analysis

TLDR
POEM has similar outcomes to HM and greater efficacy than PD, including treatment-related serious adverse events, and similar safety outcomes to both HM and PD.

Endoscopic Myotomy for Foregut Motility Disorders.

TLDR
Gastroesophageal reflux is not infrequent after POEM but does not seem significantly different from reflux that occurs after Heller myotomy, and POEM also seems to be effective in the treatment of spastic esophagal disorders.

Difficult peroral endoscopic myotomy: definition and management strategies

TLDR
A comprehensive review of difficult POEM is provided, focusing on its definition, risk factors, and intraoperative management strategies, and is expected to provide tips for not so experienced operators who perform POEM.

Outcome of Pneumatic Balloon Dilatation in Achalasia Cardia

TLDR
PD is safe and effective treatment modality for Achalasia, while younger patients have poor response to treatment with Pneumatic Dilatation, while predilatation Lower Esophageal Sphincter pressure, gender and type of achalasia did not affect the treatment outcome.

Anterior versus posterior approach in peroral endoscopic myotomy (POEM): a systematic review and meta-analysis.

TLDR
Anterior and posterior myotomy in POEM seem comparable to each other in terms of clinical success, gastroesophageal reflux disease (GERD), and adverse events.

Peroral Endoscopic Myotomy for Esophageal Motility Disorders

TLDR
Currently, POEM is a representative procedure of natural orifice transluminal endoscopic surgery, which has shown a good clinical efficacy with low complication rates for esophageal motility disorders including achalasia, however, further studies are needed to treat non-achalasia motility disorder via POEM.

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TLDR
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TLDR
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