Permutation tests for multiple loci affecting a quantitative character.
@article{Doerge1996PermutationTF, title={Permutation tests for multiple loci affecting a quantitative character.}, author={R. Doerge and G. Churchill}, journal={Genetics}, year={1996}, volume={142 1}, pages={ 285-94 } }
The problem of detecting minor quantitative trait loci (QTL) responsible for genetic variation not explained by major QTL is of importance in the complete dissection of quantitative characters. Two extensions of the permutation-based method for estimating empirical threshold values are presented. These methods, the conditional empirical threshold (CET) and the residual empirical threshold (RET), yield critical values that can be used to construct tests for the presence of minor QTL effects… CONTINUE READING
1,090 Citations
Accounting for variability in the use of permutation testing to detect quantitative trait loci.
- Mathematics, Medicine
- Biometrics
- 2000
- 69
A Model Selection Approach for the Identification of Quantitative Trait Loci in Experimental Crosses, Allowing Epistasis
- Biology, Medicine
- Genetics
- 2009
- 138
- PDF
Mapping of multiple quantitative trait loci by simple regression in half-sib designs.
- Biology, Medicine
- Journal of animal science
- 2001
- 83
Statistical method for mapping QTLs for complex traits based on two backcross populations
- Biology, Medicine
- Chinese science bulletin = Kexue tongbao
- 2012
- 2
- PDF
ON TESTING FOR SIGNIFICANT QUANTITATIVE TRAIT LOCI (QTL) EFFECTS WHEN VARIANCES ARE UNEQUAL
- Biology
- 2010
- Highly Influenced
- PDF
Detection of closely linked multiple quantitative trait loci using a genetic algorithm.
- Biology, Medicine
- Genetics
- 2001
- 47
- PDF
Enhanced efficiency of quantitative trait loci mapping analysis based on multivariate complexes of quantitative traits.
- Biology, Medicine
- Genetics
- 2001
- 132
- PDF
Model selection for quantitative trait loci mapping in a full-sib family
- Biology, Medicine
- Genetics and molecular biology
- 2012
- 6
- PDF
A Unified Semiparametric Framework for Quantitative Trait Loci Analyses, With Application to Spike Phenotypes
- Mathematics
- 2007
- 17
- Highly Influenced
- PDF
References
SHOWING 1-10 OF 51 REFERENCES
Aspects of maximum likelihood methods for the mapping of quantitative trait loci in line crosses
- Biology
- 1992
- 114
- PDF
Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1993
- 1,089
- PDF
High resolution of quantitative traits into multiple loci via interval mapping.
- Biology, Medicine
- Genetics
- 1994
- 1,039
- PDF
A simple regression method for mapping quantitative trait loci in line crosses using flanking markers
- Biology, Medicine
- Heredity
- 1992
- 1,926
- PDF
Controlling the type I and type II errors in mapping quantitative trait loci.
- Biology, Medicine
- Genetics
- 1994
- 255
- PDF
Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms
- Biology, Medicine
- Nature
- 1988
- 1,491
- PDF
Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.
- Biology, Medicine
- Genetics
- 1989
- 3,905
- PDF