Permutation tests for joinpoint regression with applications to cancer rates.

  title={Permutation tests for joinpoint regression with applications to cancer rates.},
  author={Hyune-Ju Kim and Michael P Fay and Eric J. Feuer and Douglas N Midthune},
  journal={Statistics in medicine},
  volume={19 3},
The identification of changes in the recent trend is an important issue in the analysis of cancer mortality and incidence data. We apply a joinpoint regression model to describe such continuous changes and use the grid-search method to fit the regression function with unknown joinpoints assuming constant variance and uncorrelated errors. We find the number of significant joinpoints by performing several permutation tests, each of which has a correct significance level asymptotically. Each p… CONTINUE READING
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