Permutation and parametric tests for effect sizes in voxel-based morphometry of gray matter volume in brain structural MRI.

@article{Dickie2015PermutationAP,
  title={Permutation and parametric tests for effect sizes in voxel-based morphometry of gray matter volume in brain structural MRI.},
  author={David Alexander Dickie and Shadia Mikhael and Dominic Edward Job and Joanna M. Wardlaw and David H. Laidlaw and Mark E. Bastin},
  journal={Magnetic resonance imaging},
  year={2015},
  volume={33 10},
  pages={1299-1305}
}
Permutation testing has been widely implemented in voxel-based morphometry (VBM) tools. However, this type of non-parametric inference has yet to be thoroughly compared with traditional parametric inference in VBM studies of brain structure. Here we compare both types of inference and investigate what influence the number of permutations in permutation testing has on results in an exemplar study of how gray matter proportion changes with age in a group of working age adults. High resolution T1… CONTINUE READING
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