Permissive action of protein kinase C-zeta in insulin-induced CD36- and GLUT4 translocation in cardiac myocytes.

@article{Luiken2009PermissiveAO,
  title={Permissive action of protein kinase C-zeta in insulin-induced CD36- and GLUT4 translocation in cardiac myocytes.},
  author={Joost J. F. P. Luiken and D Margriet Ouwens and Daphna D. J. Habets and Gerard C. M. van der Zon and Will A. Coumans and Robert Wolfgang Schwenk and Arend Bonen and Jan F. C. Glatz},
  journal={The Journal of endocrinology},
  year={2009},
  volume={201 2},
  pages={199-209}
}
Insulin stimulates cardiac long-chain fatty acid (LCFA) and glucose uptake via translocation of human homolog of rat fatty acid translocase (CD36) and GLUT4 respectively, from intracellular membrane compartments to the sarcolemma, a process dependent on the activation of phosphatidylinositol-3 kinase. To identify downstream kinases of insulin signaling involved in translocation of CD36 and GLUT4 in the heart, we tested i) which cardiac protein kinase C (PKC) isoforms (alpha, delta, epsilon or… CONTINUE READING

Connections & Topics

Mentioned Connections BETA
Insulin stimulates cardiac long - chain fatty acid ( LCFA ) and glucose uptake via translocation of human homolog of rat fatty acid translocase ( CD36 ) and GLUT4 respectively , from intracellular membrane compartments to the sarcolemma , a process dependent on the activation of phosphatidylinositol-3 kinase .
Insulin stimulates cardiac long - chain fatty acid ( LCFA ) and glucose uptake via translocation of human homolog of rat fatty acid translocase ( CD36 ) and GLUT4 respectively , from intracellular membrane compartments to the sarcolemma , a process dependent on the activation of phosphatidylinositol-3 kinase .
All Topics